Scottie Wilbekin had 14 points and eight assists, Pat Young recorded his sixth double-double of the season and No. 7 Florida handled No. 25 Kentucky 69-52 on Tuesday night.
The Gators (20-3, 10-1 Southeastern Conference) snapped a five-game losing streak in the series, and coach Billy Donovan improved to 2-7 against Kentucky's John Calipari.
This one solidified Florida's spot atop the league standings.
The Wildcats (17-7, 8-3) lost for the first time in six games, and it may have been costly.
Nerlens Noel, the nation's leading shot-blocker, injured his left knee in the second half and did not return.
Noel, a freshman who averages 10.6 points, 9.6 rebounds and 4.5 blocks a game for the defending national champions, landed awkwardly on his leg with about 8 minutes to play. He screamed in pain as trainers rushed to his side. Teammates carried him to the locker room for tests.
Florida had a comfortable lead before the injury.
The Gators opened a double-digit lead, 31-19, in the first half on consecutive 3-pointers by Wilbekin, Mike Rosario and Kenny Boynton.
Young and fellow big man Erik Murphy, who was in early foul trouble, carried the load in the second half.
Young made a basket with a nifty, up-and-under move, had a reverse layup and added a sweet, left-handed hook. He finished with 12 points, 11 rebounds and four blocks.
The Gators knew he had to have a big game considering they played a second game without forward Will Yeguete and were undersized against the Wildcats.
But the difference was guard play.
Wilbekin sliced through the lane at will, creating open shots for teammates and getting Kentucky's players out of position. Noel, Archie Goodwin and Willie Cauley-Stein spent time on the bench in foul trouble.